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Biomacromolecule-Tagged Nanoscale Constructs for Crossing the Blood-Brain Barrier

Odom, T.L., LeBroc, H.D., and C.E. Callmann*

Nanoscale 2024


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In Vivo Behavior of Ultrasmall Spherical Nucleic Acids

Callmann, C.E., Vasher, M.K., Das, A., Kusmierz, C.D., and C.A. Mirkin*

Small 2023

DOI: 10.1002/smll.202300097

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Transferrin Aptamers Increase the In Vivo Blood–Brain Barrier Targeting of Protein Spherical Nucleic Acids

Kusmierz, C.D., Callmann, C.E., Kudruk, S., Distler, M.E., and C.A. Mirkin

Bioconjugate Chemistry 2023

DOI: 10.1021/acs.bioconjchem.2c00389



Synergistic Immunostimulation through the Dual Activation of Toll-like Receptor 3/9 with Spherical Nucleic Acids

Huang, Z.N., Callmann, C.E., Cole, L.E., Wang, S., and C.A. Mirkin*

ACS Nano, 2021

DOI: 10.1021/acsnano.1c03093



Controlling the Biological Fate of Liposomal Spherical Nucleic Acids Using Tunable Polyethylene Glycol Shells

Wang, Z., Callmann, C.E., and C.A. Mirkin*

ACS Applied Materials and Interfaces, 2021

DOI: 10.1021/acsami.1c12852

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Rational Vaccinology: Harnessing Nanoscale Chemical Design for
Cancer Immunotherapy

Huang, Z., Callmann, C.E., Wang, S., Vasher, M.K., Evangelopoulos, M., Petrosko, S.H., and C.A. Mirkin*

ACS Central Science, 2022

DOI: 10.1021/acscentsci.2c00227

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Tumor-Associated Enzyme-Activatable Spherical Nucleic Acids

Zhang, W., Callmann, C.E., Meckes, B., and C.A. Mirkin*

ACS Nano 2022

DOI: 10.1021/acsnano.2c03323

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Disrupting the Interplay between Programmed Cell Death Protein 1 and Programmed Death Ligand 1 with Spherical Nucleic Acids in Treating Cancer

Chou, L., Callmann, C.E., Dominguez, D., Zhang, B.*, and C.A. Mirkin*

ACS Central Science 2022

DOI: 10.1021/acscentsci.2c00717



Impact of Liposomal Spherical Nucleic Acid Structure on Immunotherapeutic Function

Callmann, C.E., Kusmierz, C.D., Dittmar, J.W., Broger, L., and C.A. Mirkin*

ACS Central Science, 2021

DOI: 10.1021/acscentsci.1c00181

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Tumor Cell Lysate-Loaded Immunostimulatory Spherical Nucleic Acids as Therapeutics for Triple-Negative Breast Cancer

Callmann, C.E., Cole, L.E., Kusmierz, C.D., Huang, Z., Horiuchi, D, and C.A. Mirkin*

Proceedings of the National Academy of Sciences, 2020

DOI: 10.1073/pnas.2005794117



Paclitaxel-Terminated Peptide Brush Polymers

Zhu, J., Sun, H., Callmann, C.E., Thompson, M.P., Battistella, C., Proetto, M.T., Carlini, A.S., and N.C. Gianneschi*

Chemical Communications, 2020

DOI: 10.1039/C9CC10023G

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Defining the Design Parameters for In Vivo Enzyme Delivery Through Protein Spherical Nucleic Acids

Kusmierz, C., Bujold, K., Callmann, C.E., and C.A. Mirkin*

ACS Central Science, 2020

DOI: 10.1021/acscentsci.0c00313

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Poly(peptide): Synthesis, Structure, and Function of Peptide–Polymer Amphiphiles and Protein-like Polymers

Callmann, C.E., Thompson, M.P., and N.C. Gianneschi*

Accounts of Chemical Research, 2020

DOI: 10.1021/acs.accounts.9b00518

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Sequence Multiplicity within Spherical Nucleic Acids

Huang, Z., Cole, L.E., Callmann, C.E., Wang, S., and C.A. Mirkin*

ACS Nano, 2020

DOI: 10.1021/acsnano.9b08750

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Antitumor Activity of Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin

Callmann, C.E., LeGuyader, C.L., Burton, S., Thompson, M.P., Hennis, R.H., Barback, C.V., Henrickson, N.M., Chan, W.C., Jeremko, M.J., Yang, J., Garcia, A., Burkart, M.D., Gilson, M., Momper, J.D., Bertin, P.A., and N.C. Gianneschi*

Journal of the American Chemical Society, 2019

DOI: 10.1021/jacs.9b04272

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Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme-Directed Assembly

Battistella, C.†, Callmann, C.E.†, Thompson, M.P., Yao, S., Hayashi, T., Carson, D.A., and N.C. Gianneschi*

Advanced Healthcare Materials, 2019

DOI: 10.1002/adhm.201901105

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Tumor Retention of Enzyme-Responsive Pt(II) Drug-Loaded Nanoparticles Imaged by NanoSIMS and Fluorescence Microscopy

Proetto, M.P., Callmann, C.E., Cliff, J., Szymanski, C.J., Hu, D., Evans, J.E.; Orr, G., Howell, S.B., and N.C. Gianneschi*

ACS Central Science, 2018

DOI: 10.1021/acscentsci.8b00444



Micellar Thrombin-Binding Aptamers: Reversible Nanoscale Anticoagulants

Roloff, A., Carlini, A.S., Callmann, C.E., and N.C. Gianneschi*

Journal of the American Chemical Society, 2017

DOI: 10.1021/jacs.7b07799



Enzyme-Responsive Nanoparticles for the Treatment of Disease

Callmann, C.E. and N.C. Gianneschi*

Methods in Molecular Biology, 2017

DOI: 10.1007/978-1-4939-6840-4_15



Enzyme-Responsive Nanoparticles Release Cargo Upon Exposure to Matrix Metalloproteinase and Reactive Oxygen Species

Daniel, K.B.†, Callmann, C.E.†, Cohen, S.M.*, and N.C. Gianneschi*

Chemical Communications, 2016

DOI: 10.1039/c5cc09164k



Therapeutic Enzyme-Responsive Nanoparticles for Targeted Delivery and Accumulation in Tumors

Callmann, C.E., Barback, C.V., Thompson, M.P., Hall, D.J., Mattrey, R.F., and N.C. Gianneschi*

Advanced Materials, 2015

DOI: 10.1002/adma.201501803



Stimuli-Responsive Nanomaterials for Biomedical Applications

Blum, A. P., Kammeyer, J. K.†, Rush, A. M.†, Callmann, C. E., Hahn, M. E., and N.C. Gianneschi*

Journal of the American Chemical Society, 2015

DOI: 10.1021/ja510147n

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